Senior/Principal Scientist – Oligonucleotide Chemistry (US/China)

Contract Type:

Permanent

Location:

Shanghai, China

Date Published:

12-Feb-2026

Salary:

A rapidly growing, well-funded biotech is seeking a Senior/Principal Scientist in Oligonucleotide Chemistry and Technology (based in Boston/East Coast of United States or China) to advance RNA therapeutics from discovery into the clinic.

Key Focus
  • Lead oligonucleotide (siRNA/ASO) chemistry programs from early discovery to development
  • Drive innovation in oligo chemistry, conjugation strategies, and targeted delivery
  • Oversee and collaborate with global CROs and external partners
  • Support IP strategy and transition of novel modalities into development

Requirements

  • PhD in Organic Chemistry or related field
  • Deep expertise in oligonucleotide, nucleoside, and nucleotide chemistry
  • Proven leadership in RNA drug discovery environments
  • Fluent in English and Mandarin (bilingual capability required) and comfortable operating at the interface of China and global R&D teams
  • Able to work effectively across global, cross-cultural teams


Senior candidates based in the US or China who are passionate about next-generation RNA therapeutics are encouraged to apply or enquire confidentially.


BeathChapman Pte Ltd
Apply Now

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