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Job Details

Location
Singapore
Salary
Permanent Role with 2 Months Fixed Bonus + Performance Bonus
Job Type
Permanent
Ref
BH-165143
Contact
Weiyan Woo
Contact email
Email Weiyan
Contact phone
65 6692 9346
Posted
about 2 months ago
  • Up to $10000 + Fixed Allowancs $700
  • Permanent Role with 2 Months Fixed Bonus + Performance Bonus
  • MNC Research Lab, Located at Central near MRT stations
  • Experiences in In Vitro Research / Toxicology Studies
  • Experiences in Leading R&D Team and Projects 
Responsibilities:
  • Lead a team of technicians responsible for the establishment and execution of in vitro toxicology and pharmacology studies such as microbial mutagenicity assays, as well as cell-based cytotoxicity and genotoxicity assays, in accordance with the OECD GLP requirements.
  • The team will also be responsible for providing downstream cell and biochemical assay development, validation and analysis services to support the organization’s in vivo study execution, which includes a battery of clinical pathology assays, flow cytometry and ELISA assays.
  • Lead the organizational effort in developing and implementing state-of-the-art organotypic cultures or organ-on-a-chip technology to advance the regulatory-compliant ready research capability in line with the 3Rs principle of animal research adopted by the organization.
  • Oversee the overall activities in the Cell Bioassays laboratories to ensure SOP/technical guides and training are available and adequate for the technicians to perform their day to day tasks.
  • Responsible for establishing, maintaining and improving the organization’s technical expertise in the domain of in vitro toxicology and genotoxicology, keeping up with scientific and regulatory advancement in the field. This may include, but not be limited to microbial mutagenesis assay (Ames), cell-based viability assays (neutral red uptake) or mutagenesis assays (mouse lymphoma assay, micronucleus assay).
  • Keep track with technological advancement in the field, assess, adopt and provide expertise for developing and implementing new/innovative techniques, assays, methods, capabilities that will enable/accelerate organization’s scientific project portfolio execution and/or will meet external client needs.
  • Act as Study Director for in vitro toxicology and pharmacology studies, which includes being responsible for the overall scientific conduct of the study, from conceptualization to closure. Plans, manages and reports the studies in accordance with pertinent regulatory guidelines (i.e. OECD GLP Principles and Test Guidelines) and to customer's satisfaction.
  • Represent the function to coordinate and liaise with cross-functional units and stakeholders on the planning, resourcing, execution, data analysis and reporting of relevant study phase (i.e. clinical pathology, flow cytometry and biochemical assays) for in vivo pre-clinical studies.
Requirements:

  • Postgraduate degree in Biology, Life Sciences or related scientific discipline, Ph.D. preferred.
  • Minimum 5 years of relevant professional experience, with in-depth scientific knowledge focusing on in vitro research and/or toxicology studies with a CRO, R&D unit within life science industry, or translational academic research organizations, preferably in a regulated environment.
  • Able to develop/optimize/validate cell-based and/or microbiological assays independently.
  • Experience in leading R&D team and projects.
  • Understanding of regulatory guidelines such as FDA, ICH, OECD GLP and TGs related to in vitro toxicology and genotoxicity, and quality management system is preferred.
  • Self-starter and highly motivated individual with excellent communication and influencing skills.
Interested candidates can forward their CVs in MS Word format to weiyan@connect-ebc.com


Reg No. R1983718
EBC Connect Pte Ltd
Licence no. 17C8975